Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360081 | 0.89 | PDE5A (0.83) | PDE5A | |
| SCHEMBL8363071 | 0.81 | PDE5A (0.54) | PDE5A | |
| SCHEMBL8358726 | 0.79 | PDE5A (1.00) | PDE5A | |
| SCHEMBL8358716 | 0.79 | PDE5A (1.00) | PDE5A | |
| SCHEMBL8360100 | 0.79 | PDE5A (0.84) | PDE5A | |
| SCHEMBL16313334 | 0.79 | PDE5A (0.52) | PDE5A | |
| SCHEMBL8360096 | 0.78 | PDE5A (0.90) | PDE5A | |
| SCHEMBL8360067 | 0.77 | PDE5A (0.77) | PDE5A | |
| SCHEMBL8360102 | 0.77 | PDE5A (0.81) | PDE5A | |
| SCHEMBL13409588 | 0.77 | PDE5A (0.75) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020724-A1 | POLYCYCLIC GUANINE PHOSPHODIESTERASE V INHIBITORS | SCHERING CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |