SCHEMBL16316701

SCHEMBL16316701

CCCOc1ccc(C(NC(=O)OCC2c3ccccc3-c3ccccc32)c2ccc(OC)cc2OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ MDM2 Q00987 1/20 0.41
▸ ACACB O00763 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ CASP3 P42574 1/20 0.39
▸ PIK3CG P48736 1/20 0.39
▸ FABP5 Q01469 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12873284 0.94 LMNA (0.46) KMT2AMEN1MDM2LMNACASP3
SCHEMBL12555211 0.92 KMT2A (0.47) KMT2AMEN1MDM2CASP3FABP5
SCHEMBL7772788 0.91 KMT2A (0.46) KMT2AMEN1MDM2HPGDCASP3
SCHEMBL13523948 0.91 KMT2A (0.46) KMT2AMEN1MDM2HPGDCASP3
SCHEMBL3367289 0.89 KMT2A (0.45) KMT2AMEN1MDM2LMNAHPGD
SCHEMBL14416300 0.89 KMT2A (0.42) KMT2AMEN1MDM2LMNAHPGD
SCHEMBL20143503 0.89 KMT2A (0.42) KMT2AMEN1MDM2LMNACASP3
SCHEMBL1745934 0.89 KMT2A (0.45) KMT2AMEN1MDM2LMNAHPGD
SCHEMBL31146900 0.89 KMT2A (0.45) KMT2AMEN1MDM2LMNAHPGD
SCHEMBL29470540 0.89 KMT2A (0.45) KMT2AMEN1MDM2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7528104-B2 Peptides that bind to the erythropoietin receptor AFFYMAX, INC. (US) 2009-05-05 — — US disclosed
US-20070027074-A1 Novel peptides that bind to the erythropoietin receptor AFFYMAX, INC. (US) 2007-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027074-A1 Novel peptides that bind to the erythropoietin receptor EPOR, PROKR1, EDNRB KMT2A 4517/4885MEN1 3831/4885MDM2 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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