Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | PIR | O00625 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17020444 | 1.00 | CYP2C19 (0.79) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL17015173 | 0.89 | CYP2C19 (1.00) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL16317067 | 0.89 | CYP2C19 (1.00) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL1774769 | 0.83 | CYP2C19 (0.54) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL1774767 | 0.83 | CYP2C19 (0.54) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL2938712 | 0.83 | CYP2C19 (0.54) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL1774945 | 0.81 | CYP2C19 (0.84) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL1774946 | 0.81 | CYP2C19 (0.84) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL2940445 | 0.81 | CYP2C19 (0.84) | CYP2C19MEN1KMT2APIRALDH1A1 | |
| SCHEMBL30435139 | 0.81 | MEN1 (0.58) | CYP2C19MEN1KMT2APIRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058358-A1 | SULPHIMIDES AS PROTEIN KINASE INHIBITORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058358-A1 | SULPHIMIDES AS PROTEIN KINASE INHIBITORS | PRKCE, BRAF, PACSIN2 | CYP2C19 3401/4885MEN1 2173/4885KMT2A 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.