Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319152 | 0.93 | PPARD (0.50) | PPARDTSHRMAPTCA12CA1 | |
| SCHEMBL4942141 | 0.87 | KMT2A (0.47) | PPARDTSHRGPR84FFAR1FFAR4 | |
| SCHEMBL10431817 | 0.87 | KMT2A (0.47) | PPARDTSHRGPR84FFAR1FFAR4 | |
| SCHEMBL7616579 | 0.85 | KMT2A (0.44) | PPARDTSHRGPR84FFAR1FFAR4 | |
| SCHEMBL14549069 | 0.82 | PPARD (0.57) | PPARDKDM4ESMN1; SMN2TSHRGPR84 | |
| SCHEMBL10049892 | 0.81 | GPR84 (0.40) | KDM4ESMN1; SMN2TSHRGPR84FFAR1 | |
| SCHEMBL3586482 | 0.81 | TSHR (0.47) | PPARDKDM4ETSHRKMT2ACA12 | |
| SCHEMBL2371044 | 0.79 | TSHR (0.46) | PPARDTSHRMAPTCA12CA1 | |
| SCHEMBL18250731 | 0.78 | TSHR (0.55) | PPARDTSHRMAPTCA12CA1 | |
| SCHEMBL1497353 | 0.76 | TSHR (0.43) | PPARDKDM4ETSHRMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2816049-B1 | ß-ketophosphonic acids and all dental materials based thereon | IVOCLAR VIVADENT AG (LI) | 2018-05-30 | — | — | EP | disclosed |
| US-9783559-B2 | β-Ketophosphonic acids and dental materials based thereon | IVOCLAR VIVADENT AG (LI) | 2017-10-10 | — | — | US | disclosed |
| US-9783559-B2 | β-Ketophosphonic acids and dental materials based thereon | IVOCLAR VIVADENT AG (LI) | 2017-10-10 | — | — | US | disclosed |
| US-9783559-B2 | β-Ketophosphonic acids and dental materials based thereon | IVOCLAR VIVADENT AG (LI) | 2017-10-10 | — | — | US | disclosed |
| US-20160145277-A1 | B-Ketophosphonic Acids And Dental Materials Based Thereon | IVOCLAR VIVADENT AG (LI) | 2016-05-26 | — | — | US | disclosed |
| US-20160145277-A1 | B-Ketophosphonic Acids And Dental Materials Based Thereon | IVOCLAR VIVADENT AG (LI) | 2016-05-26 | — | — | US | disclosed |
| CN-105283460-A | [Beta]-ketophosphonic acids and dental materials based thereon | IVOCLAR VIVADENT AG | 2016-01-27 | — | — | CN | disclosed |
| WO-2014202176-A1 | ß-KETOPHOSPHONIC ACIDS AND DENTAL MATERIALS BASED THEREON | IVOCLAR VIVADENT AG (LI) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014202176-A1 | ß-KETOPHOSPHONIC ACIDS AND DENTAL MATERIALS BASED THEREON | IVOCLAR VIVADENT AG (LI) | 2014-12-24 | — | — | WO | disclosed |
| EP-2816049-A1 | ß-ketophosphonic acids and all dental materials based thereon | Ivoclar Vivadent AG (LI) | 2014-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145277-A1 | B-Ketophosphonic Acids And Dental Materials Based Thereon | CYP2B6, GRM6, VKORC1 | PPARD 1522/4885KDM4E 2909/4885SMN1; SMN2 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.