Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.57 |
| ▸ | AR | P10275 | 5/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629244 | 0.85 | PGR (1.00) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1631165 | 0.83 | PGR (0.78) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1631937 | 0.81 | PGR (0.71) | PGRNR3C1NR3C2ARKDM1A | |
| SCHEMBL3380147 | 0.78 | PGR (0.44) | PGRNR3C1NR3C2ARBRPF1 | |
| SCHEMBL1630484 | 0.78 | PGR (0.69) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1630849 | 0.75 | PGR (0.69) | PGRNR3C1NR3C2ARKDM1A | |
| SCHEMBL1630685 | 0.75 | PGR (0.65) | PGRNR3C1NR3C2ARKDM1A | |
| SCHEMBL1632336 | 0.74 | PGR (0.76) | PGRNR3C1NR3C2ARKDM1A | |
| SCHEMBL1630550 | 0.74 | PGR (0.78) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1631503 | 0.73 | PGR (0.78) | PGRNR3C1NR3C2ARBRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932284-B2 | Indole sulfonamide modulators of progesterone receptors | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |