Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2496110 | 0.85 | FFAR1 (0.39) | FFAR1PDE10A | |
| SCHEMBL16326395 | 0.84 | FFAR1 (0.38) | MAPK14FFAR1PDE10A | |
| SCHEMBL2495802 | 0.84 | CA1 (0.38) | MAPK14GCKFFAR1MEN1ALDH1A1 | |
| SCHEMBL2495931 | 0.83 | FFAR1 (0.38) | MAPK14FFAR1CCNT1CDK9PDE10A | |
| SCHEMBL12192000 | 0.81 | FFAR1 (0.36) | FFAR1PDE10A | |
| SCHEMBL16318626 | 0.81 | ELANE (0.35) | MAPK14GCKFFAR1 | |
| SCHEMBL16318931 | 0.74 | NPC1 (0.45) | TNIKESR1MEN1ALDH1A1APP | |
| SCHEMBL19175041 | 0.73 | SUV39H2 (0.41) | MAPK14GCKPIK3CDPIK3CACCNT1 | |
| SCHEMBL16319178 | 0.73 | FFAR1 (0.34) | TNIKFFAR1ESR1MEN1ALDH1A1 | |
| SCHEMBL16319110 | 0.71 | FFAR1 (0.41) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |