Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319227 | 0.82 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL16318931 | 0.75 | NPC1 (0.45) | — | |
| SCHEMBL2314294 | 0.72 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL2500456 | 0.72 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL12220721 | 0.72 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL16319135 | 0.71 | MAPK14 (0.35) | FFAR1 | |
| SCHEMBL12221714 | 0.71 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL12220308 | 0.71 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL12220277 | 0.71 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL2498615 | 0.71 | ALDH1A1 (0.45) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |