Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318904 | 0.89 | F10 (0.41) | F10FFAR1TP53F2PRSS1 | |
| SCHEMBL18501546 | 0.85 | F10 (0.39) | F10FFAR1TP53F2PRSS1 | |
| SCHEMBL17428337 | 0.84 | OPRD1 (0.44) | F10FFAR1ALDH1A1FFAR2 | |
| SCHEMBL17418579 | 0.84 | OPRD1 (0.44) | F10FFAR1ALDH1A1FFAR2 | |
| SCHEMBL17428343 | 0.84 | OPRD1 (0.44) | F10FFAR1ALDH1A1FFAR2 | |
| SCHEMBL16318614 | 0.83 | FFAR1 (0.38) | F10FFAR1TP53F2PRSS1 | |
| SCHEMBL18506432 | 0.83 | MAPT (0.38) | F10FFAR1F2PRSS1ALDH1A1 | |
| SCHEMBL18506430 | 0.83 | MAPT (0.38) | F10FFAR1F2PRSS1ALDH1A1 | |
| SCHEMBL12193231 | 0.79 | OPRD1 (0.42) | FFAR1TP53ALDH1A1TSHR | |
| SCHEMBL12193233 | 0.79 | OPRD1 (0.42) | FFAR1TP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |