Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318838 | 0.87 | PIK3CD (0.36) | PIK3CDPIK3CBALDH1A1HPGDHSD17B10 | |
| SCHEMBL16319268 | 0.75 | GUSB (0.41) | GUSBALDH1A1TNIKFFAR1MAPT | |
| SCHEMBL16318931 | 0.73 | NPC1 (0.45) | ALDH1A1HSD17B10LMNATNIKTSHR | |
| SCHEMBL16318872 | 0.70 | GUSB (0.41) | GUSBTNIKMAPTSMN1; SMN2 | |
| SCHEMBL16318965 | 0.70 | PTPN1 (0.41) | ALDH1A1HPGDHSD17B10KDM4ETNIK | |
| SCHEMBL16319224 | 0.70 | FFAR1 (0.40) | PIK3CDPIK3CBTNIKFFAR1 | |
| SCHEMBL16318590 | 0.69 | FFAR1 (0.48) | ALDH1A1TNIKFFAR1GAA | |
| SCHEMBL16318775 | 0.69 | FFAR1 (0.43) | ALDH1A1TNIKFFAR1GAA | |
| SCHEMBL16318940 | 0.68 | FFAR1 (0.41) | TNIKFFAR1 | |
| SCHEMBL16318863 | 0.67 | FFAR1 (0.38) | ALDH1A1FFAR1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |