Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP8 | P40818 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318905 | 0.85 | FFAR1 (0.33) | FFAR1CA12CA1CA9PIK3CD | |
| SCHEMBL16319224 | 0.82 | FFAR1 (0.40) | FFAR1PIK3CDPIK3CB | |
| SCHEMBL16318652 | 0.80 | SMN1; SMN2 (0.32) | FFAR1CA12CA1CA9MEN1 | |
| SCHEMBL16319169 | 0.80 | BACE1 (0.33) | FFAR1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL16319029 | 0.76 | CA12 (0.39) | CA12CA1CA9 | |
| SCHEMBL16318919 | 0.73 | FFAR1 (0.43) | FFAR1KDM1A | |
| SCHEMBL2501349 | 0.72 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL26978693 | 0.72 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL16318790 | 0.70 | IDO1 (0.35) | FFAR1CA12CA1CA9MAPT | |
| SCHEMBL4979875 | 0.69 | CA12 (0.43) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |