Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318652 | 0.98 | SMN1; SMN2 (0.32) | BACE1SMN1; SMN2NPSR1FFAR1APP | |
| SCHEMBL16319294 | 0.82 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL16319289 | 0.80 | FFAR1 (0.34) | SMN1; SMN2NPSR1FFAR1MEN1MAPT | |
| SCHEMBL16319250 | 0.80 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL16318905 | 0.80 | FFAR1 (0.33) | NPSR1FFAR1MEN1MAPTKMT2A | |
| SCHEMBL16318804 | 0.79 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL16318844 | 0.78 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL16319189 | 0.77 | CA12 (0.37) | BACE1 | |
| SCHEMBL16318884 | 0.76 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL16319117 | 0.71 | CNR1 (0.35) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |