Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319739 | 0.85 | AR (0.78) | AR | |
| SCHEMBL16319486 | 0.81 | AR (0.61) | ARPLA2G7 | |
| SCHEMBL10244458 | 0.81 | AR (0.56) | ARPLA2G7 | |
| SCHEMBL12806908 | 0.77 | SCN9A (0.46) | ARPLA2G7 | |
| SCHEMBL12806673 | 0.77 | PPARG (0.44) | ARPLA2G7 | |
| SCHEMBL875970 | 0.77 | AR (0.54) | ARPLA2G7 | |
| SCHEMBL15096357 | 0.77 | AR (0.60) | ARPLA2G7 | |
| SCHEMBL9104268 | 0.76 | IDO1 (0.50) | ARPLA2G7 | |
| SCHEMBL365180 | 0.76 | AR (0.60) | ARPLA2G7 | |
| SCHEMBL16319405 | 0.76 | BRAF (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |