Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.61 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.52 |
| ▸ | ESRRA | P11474 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319739 | 0.86 | AR (0.78) | AR | |
| SCHEMBL15096357 | 0.86 | AR (0.60) | ARPLA2G7 | |
| SCHEMBL16319482 | 0.82 | AR (0.55) | ARPLA2G7 | |
| SCHEMBL17219858 | 0.81 | AR (0.71) | ARPLA2G7 | |
| SCHEMBL16319334 | 0.81 | AR (0.59) | ARPLA2G7 | |
| SCHEMBL11855441 | 0.81 | AR (0.55) | AR | |
| SCHEMBL24998718 | 0.79 | AR (0.57) | ARPLA2G7 | |
| SCHEMBL875634 | 0.78 | AR (0.60) | ARPLA2G7 | |
| SCHEMBL28696659 | 0.78 | PLA2G7 (0.67) | ARPLA2G7 | |
| SCHEMBL876881 | 0.78 | AR (0.60) | ARPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |