Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.63 |
| ▸ | AR | P10275 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630745 | 0.90 | PGR (0.67) | PGRNR3C1NR3C2ARHPGD | |
| SCHEMBL1630789 | 0.86 | PGR (0.70) | PGRNR3C1NR3C2ARHPGD | |
| SCHEMBL1629963 | 0.85 | PGR (0.69) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1630826 | 0.82 | PGR (0.74) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1631048 | 0.80 | PGR (0.74) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1631091 | 0.80 | PGR (0.73) | PGRNR3C1NR3C2ARHPGD | |
| SCHEMBL1630275 | 0.80 | PGR (0.62) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1629329 | 0.78 | PGR (0.71) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1629465 | 0.78 | PGR (0.71) | PGRNR3C1NR3C2ARSCN9A | |
| SCHEMBL1629927 | 0.78 | PGR (0.71) | PGRNR3C1NR3C2ARSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932284-B2 | Indole sulfonamide modulators of progesterone receptors | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |