Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319782 | 0.88 | CHRM1 (0.41) | CHRM1KCNH2LMNA | |
| SCHEMBL1227363 | 0.85 | CHRM1 (0.47) | CHRM1KCNH2DRD4 | |
| SCHEMBL1228587 | 0.82 | CHRM1 (0.42) | CHRM1KCNH2MEN1KMT2ALMNA | |
| SCHEMBL1226690 | 0.81 | CHRM1 (0.48) | CHRM1KCNH2 | |
| SCHEMBL1228728 | 0.79 | CHRM1 (0.47) | CHRM1KCNH2CYP4F2CYP4A11ADORA3 | |
| SCHEMBL1228519 | 0.79 | CHRM1 (0.59) | CHRM1KCNH2DRD4 | |
| SCHEMBL1227949 | 0.78 | KCNH2 (0.43) | CHRM1KCNH2 | |
| SCHEMBL1227806 | 0.77 | CHRM1 (0.42) | CHRM1KCNH2MEN1KMT2ALMNA | |
| SCHEMBL1227270 | 0.76 | CHRM1 (0.56) | CHRM1KCNH2 | |
| SCHEMBL1227259 | 0.76 | KCNH2 (0.55) | CHRM1KCNH2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459570-B1 | NITROIMIDAZOOXAZINE ANALOGUES AND THEIR USES | GLOBAL ALLIANCE FOR TB DRUG DEV (US) | 2014-12-24 | — | — | EP | disclosed |