Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319648 | 0.88 | CHRM1 (0.35) | CHRM1KCNH2LMNA | |
| SCHEMBL1228519 | 0.85 | CHRM1 (0.59) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL1228587 | 0.85 | CHRM1 (0.42) | CHRM1KCNH2LMNA | |
| SCHEMBL1227949 | 0.85 | KCNH2 (0.43) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL1227270 | 0.83 | CHRM1 (0.56) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL1227363 | 0.79 | CHRM1 (0.47) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL1227806 | 0.78 | CHRM1 (0.42) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL1228715 | 0.78 | CHRM1 (0.54) | CHRM1KCNH2 | |
| SCHEMBL15442757 | 0.77 | PTGS1 (0.40) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL1226690 | 0.76 | CHRM1 (0.48) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459570-B1 | NITROIMIDAZOOXAZINE ANALOGUES AND THEIR USES | GLOBAL ALLIANCE FOR TB DRUG DEV (US) | 2014-12-24 | — | — | EP | disclosed |