Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 8/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365180 | 0.82 | AR (0.60) | ARPLA2G7KDR | |
| SCHEMBL24998871 | 0.79 | PLA2G7 (0.48) | PLA2G7SCN9A | |
| SCHEMBL9103130 | 0.78 | PLA2G7 (0.47) | PLA2G7SCN9A | |
| SCHEMBL17884205 | 0.78 | PLA2G7 (0.53) | PLA2G7SCN9A | |
| SCHEMBL25737338 | 0.78 | PLA2G7 (0.56) | PLA2G7 | |
| SCHEMBL9901518 | 0.78 | PLA2G7 (0.53) | PLA2G7 | |
| SCHEMBL9108605 | 0.78 | PLA2G7 (0.45) | PLA2G7SCN9A | |
| SCHEMBL29851798 | 0.78 | PLA2G7 (0.47) | PLA2G7SCN9A | |
| SCHEMBL365436 | 0.77 | SCN9A (0.47) | PLA2G7SCN9A | |
| SCHEMBL16319739 | 0.77 | AR (0.78) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |