SCHEMBL16320229

SCHEMBL16320229

CCCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCO)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.60
AKR1A1 P14550 1/20 0.60
CHRM3 P20309 1/20 0.60
HTR2A P28223 1/20 0.60
HTR2C P28335 1/20 0.60
ADRA1A P35348 1/20 0.60
HRH1 P35367 1/20 0.60
DRD3 P35462 1/20 0.60
SLC6A3 Q01959 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC2 Q92769 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
GRIK1 P39086 2/20 0.59
GRIK2 Q13002 2/20 0.59
CA2 P00918 2/20 0.57
MAPK1 P28482 1/20 0.57
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
GPR84 Q9NQS5 3/20 0.55
FFAR1 O14842 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4244106 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7717314 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4805985 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL115389 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6551008 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11429629 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11351799 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL3376831 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7861837 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL3166957 1.00 CHRM1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4494707-A2 OPHTHALMIC FORMULATION University of Western Sydney (AU) 2025-01-22 EP claimed
EP-3459929-A1 OPHTHALMIC FORMULATION University of Western Sydney (AU) 2019-03-27 EP claimed
EP-2794550-B1 OPHTHALMIC FORMULATION UNIV OF WESTERN SYDNEY (AU) 2019-02-20 EP claimed
CN-104271548-A Ophthalmic formulation UNIV WESTERN SYDNEY 2015-01-07 CN claimed
US-20260049049-A1 OPHTHALMIC FORMULATION WESTERN SYDNEY UNIV (AU) 2026-02-19 US disclosed
EP-4494707-A2 OPHTHALMIC FORMULATION University of Western Sydney (AU) 2025-01-22 EP disclosed
US-20240368069-A1 OPHTHALMIC FORMULATION WESTERN SYDNEY UNIV (AU) 2024-11-07 US disclosed
US-20210403410-A1 OPHTHALMIC FORMULATION WESTERN SYDNEY UNIV (AU) 2021-12-30 US disclosed
US-20200190015-A1 OPHTHALMIC FORMULATION WESTERN SYDNEY UNIV (AU) 2020-06-18 US disclosed
US-10385003-B2 Ophthalmic formulation MILLAR THOMAS (AU) 2019-08-20 US disclosed
EP-3459929-A1 OPHTHALMIC FORMULATION University of Western Sydney (AU) 2019-03-27 EP disclosed
EP-2794550-B1 OPHTHALMIC FORMULATION UNIV OF WESTERN SYDNEY (AU) 2019-02-20 EP disclosed
CN-104271548-A Ophthalmic formulation UNIV WESTERN SYDNEY 2015-01-07 CN disclosed
US-20140377335-A1 OPHTHALMIC FORMULATION UNIV WESTERN SYDNEY (AU) 2014-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190015-A1 OPHTHALMIC FORMULATION C9, C1R, F12 CHRM1 470/4885AKR1A1 87/4885CHRM3 332/4885
US-10385003-B2 Ophthalmic formulation C9, C1R, C1S CHRM1 472/4885AKR1A1 111/4885CHRM3 379/4885
US-20140377335-A1 OPHTHALMIC FORMULATION C9, C1R, C1S CHRM1 472/4885AKR1A1 111/4885CHRM3 379/4885
US-20210403410-A1 OPHTHALMIC FORMULATION C9, C1R, C5 CHRM1 1171/4885AKR1A1 195/4885CHRM3 523/4885
US-20260049049-A1 OPHTHALMIC FORMULATION HACD3, STARD3, SPTLC3 CHRM1 1222/4885AKR1A1 1876/4885CHRM3 1307/4885
US-20240368069-A1 OPHTHALMIC FORMULATION C9, C1R, F12 CHRM1 470/4885AKR1A1 87/4885CHRM3 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.