Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447233 | 0.81 | MAPT (0.40) | GAAMAPT | |
| SCHEMBL4283708 | 0.74 | GAA (0.44) | GAAMAPT | |
| SCHEMBL6056252 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL18562457 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL5470066 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL4540870 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL12159337 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL6111309 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL7442660 | 0.69 | GAA (0.44) | GAAMAPT | |
| SCHEMBL2464235 | 0.69 | GAA (0.40) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162799-B1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-03-10 | — | — | EP | disclosed |
| EP-3686182-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-20200207782-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | SUMITOMO DAINIPPON PHARMA CO., LTD (JP) | 2020-07-02 | — | — | US | disclosed |
| US-10696640-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10308613-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-9777000-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-3162799-A1 | FLUOROALKYLATING AGENT | Ihara Chemical Industry Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-20160347751-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2016-12-01 | — | — | US | disclosed |
| US-9453015-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-9440970-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2016-09-13 | — | — | US | disclosed |
| EP-2963037-A1 | NOVEL PYRAZOLE DERIVATIVE | Mochida Pharmaceutical Co., Ltd. (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-20150166536-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
| US-20150133448-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-05-14 | — | — | US | disclosed |
| US-20150132327-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-05-14 | — | — | US | disclosed |
| US-8980888-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-8980889-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140378448-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308613-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | GAA 1685/4885MAPT 4841/4885 |
| US-20150166536-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | GAA 221/4885MAPT 75/4885 |
| US-10696640-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | GAA 1685/4885MAPT 4841/4885 |
| US-20200207782-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | NR0B1, CYP4A11, CYP4B1 | GAA 2897/4885MAPT 4722/4885 |
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | GAA 221/4885MAPT 75/4885 |
| US-20160347751-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | GAA 221/4885MAPT 75/4885 |
| US-20140378448-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | GAA 221/4885MAPT 75/4885 |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | GAA 1685/4885MAPT 4841/4885 |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | GAA 1685/4885MAPT 4841/4885 |
| US-20150133448-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | GAA 221/4885MAPT 75/4885 |
| US-20150132327-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | GAA 221/4885MAPT 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.