SCHEMBL16320674

SCHEMBL16320674

CC(=O)O[C@H](CC#N)COCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 5/20 0.46
ALDH1A1 P00352 1/20 0.45
SLC1A1 P43005 1/20 0.42
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CTSL P07711 4/20 0.41
CTSK P43235 2/20 0.41
KMT2A Q03164 1/20 0.40
MMP12 P39900 1/20 0.39
GHSR Q92847 2/20 0.39
CTSB P07858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789021 0.87 ALDH1A1 (0.55) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL24827422 0.81 ALDH1A1 (0.57) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL10834752 0.81 ALDH1A1 (0.49) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL11249744 0.81 ALDH1A1 (0.49) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL9207169 0.81 ALDH1A1 (0.49) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL28507044 0.79 ALDH1A1 (0.54) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL16365942 0.78 ALDH1A1 (0.50) ALDH1A1KMT2A
SCHEMBL2080147 0.77 ALDH1A1 (0.42) ALDH1A1SLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL6582298 0.77 TSHR (0.40) CTSSSLC1A1APOBEC3AAPOBEC3GCA1
SCHEMBL27595694 0.77 TSHR (0.40) CTSSSLC1A1APOBEC3AAPOBEC3GCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014203045-A1 A NOVEL, GREEN AND COST EFFECTIVE PROCESS FOR SYNTHESIS OF TERT-BUTYL (3R,5S)-6-OXO-3,5-DIHYDROXY-3,5-O-ISOPROPYLIDENE-HEXANOATE LUPIN LIMITED (IN) 2014-12-24 WO disclosed