Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28832907 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL6685591 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL457021 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL11096099 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL15662074 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL15662076 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL18741300 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL8726959 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL11137215 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2420 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436259-B | Method and device for recovering tail gas of ethylene oxide/ethylene glycol device | 中国石油化工股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116410971-A | Immobilized enzyme carrier and preparation method thereof | 中国石油天然气股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-113578348-B | Two-dimensional in-plane heterogeneous CuS/CuO, and preparation method and application thereof | 安徽大学 | 2023-07-04 | — | — | CN | claimed |
| CN-116262704-A | Method for preparing N, N-dimethylglycine and co-producing metal chelate thereof | 万华化学集团股份有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-111978562-B | Method for emulsifying isoprene rubber glue solution | 淄博鲁华泓锦新材料集团股份有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-114681146-A | Pretreatment method for biological tissue, crosslinking modification method, biological tissue preform, and biological tissue | 杭州启明医疗器械股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-113578348-A | Two-dimensional in-plane heterogeneous CuS/CuO and preparation method and application thereof | 安徽大学 | 2021-11-02 | — | — | CN | claimed |
| CN-111978562-A | Method for emulsifying isoprene rubber glue solution | 淄博鲁华泓锦新材料股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| EP-1878469-B1 | Gel network surfactant based thickening systems for hair colourant and bleaching compositions | PROCTER & GAMBLE (US) | 2010-09-01 | — | — | EP | claimed |
| CN-101032506-A | Chinese traditional medicine composition for hemangiectasis | ZHAO HONGXIN (CN) | 2007-09-12 | — | — | CN | claimed |
| EP-0992490-B2 | Flowable formed methionine products and method for producing the same | DEGUSSA (DE) | 2007-08-29 | — | — | EP | claimed |
| EP-0799886-B1 | Laundry detergent tablets | CLEANTABS AS (DK) | 2002-11-27 | — | — | EP | claimed |
| US-20250206603-A1 | INTEGRATED SYSTEM OF DEVICES AND PROCEDURE FOR CONVERTING CARBON-BASED COMPOSITE MATERIAL INTO A HYDROGEN-RICH GAS, WITH THE OPTION OF CAPTURING AND USING ITS EMISSIONS AND WASTE | BLUEPLASMA POWER, S.L. (ES) | 2025-06-26 | — | — | US | disclosed |
| EP-4574926-A1 | INTEGRATED SYSTEM OF DEVICES AND PROCEDURE FOR CONVERTING CARBON-BASED COMPOSITE MATERIAL INTO A HYDROGEN-RICH GAS, WITH THE OPTION OF CAPTURING AND USING ITS EMISSIONS AND WASTE | Blueplasma Power, S.L. (ES) | 2025-06-25 | — | — | EP | disclosed |
| CN-118302420-A | TLR modulators and uses thereof | 映恩生物制药（苏州）有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-0023666-A1 | Anthraquinone-azomethine compounds, process for their preparation as well as a process for pigmenting organic macromolecular materials | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0013307-A1 | Liquid foliar fertilizer compositions containing water-soluble urea-formaldehyde products | ALLIED CORPORATION (US) | 1980-07-23 | — | — | EP | disclosed |
| US-4066823-A | Method for a low temperature oxygen electrode | ARMSTRONG WILLIAM A | 1978-01-03 | — | — | US | disclosed |
| US-3948684-A | Oxygen electrode and process for making the same | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) | 1976-04-06 | — | — | US | disclosed |