Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29155029 | 0.95 | — | — | |
| Bicarbonate SCHEMBL176182 | 0.95 | — | — | |
| Bicarbonate SCHEMBL11096104 | 0.95 | CA4 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL163254 | 0.95 | CA4 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL7930058 | 0.90 | CA4 (0.39) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL10525004 | 0.90 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL8441974 | 0.90 | — | — | |
| Bicarbonate SCHEMBL457021 | 0.90 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL15662076 | 0.90 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL15662074 | 0.90 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490337-A | Preparation of cupric hydroxide | KOCIDE CHEMICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |