SCHEMBL16327947

SCHEMBL16327947

N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C=O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 14/20 0.68
▸ DPP8 Q6V1X1 9/20 0.56
▸ DPP9 Q86TI2 9/20 0.56
▸ DPP7 Q9UHL4 9/20 0.56
▸ FAP Q12884 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16572508 0.88 DPP4 (0.67) DPP4DPP8DPP9DPP7FAP
SCHEMBL24448607 0.88 DPP4 (0.67) DPP4DPP8DPP9DPP7FAP
SCHEMBL29477123 0.82 DPP4 (0.68) DPP4DPP8DPP9DPP7FAP
SCHEMBL8892192 0.82 DPP4 (0.68) DPP4DPP8DPP9DPP7FAP
SCHEMBL27369439 0.82 DPP4 (0.68) DPP4DPP8DPP9DPP7FAP
SCHEMBL8892200 0.82 DPP4 (0.68) DPP4DPP8DPP9DPP7FAP
SCHEMBL5336562 0.82 DPP4 (0.68) DPP4DPP8DPP9DPP7FAP
SCHEMBL7114188 0.82 DPP4 (0.68) DPP4DPP8DPP9DPP7FAP
SCHEMBL10792312 0.81 DPP4 (0.67) DPP4DPP8DPP9DPP7FAP
SCHEMBL30423009 0.79 DPP4 (0.63) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357654-B2 Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-01-22 — — US disclosed
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-07-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CD40, CD40LG, TNFSF10 DPP4 2432/4885DPP8 2820/4885DPP9 2466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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