Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.54 |
| ▸ | FAP | Q12884 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892200 | 1.00 | DPP4 (0.68) | DPP4OPRM1OPRD1DPP8DPP9 | |
| SCHEMBL27369439 | 1.00 | DPP4 (0.68) | DPP4OPRM1OPRD1DPP8DPP9 | |
| SCHEMBL5336562 | 0.90 | DPP4 (0.68) | DPP4OPRM1OPRD1DPP8DPP9 | |
| SCHEMBL7114188 | 0.90 | DPP4 (0.68) | DPP4OPRM1OPRD1DPP8DPP9 | |
| SCHEMBL29477123 | 0.90 | DPP4 (0.68) | DPP4OPRM1OPRD1DPP8DPP9 | |
| SCHEMBL8862702 | 0.88 | DPP4 (0.67) | DPP4OPRM1DPP8DPP9DPP7 | |
| SCHEMBL6933624 | 0.88 | DPP4 (0.67) | DPP4OPRM1DPP8DPP9DPP7 | |
| SCHEMBL6092096 | 0.88 | DPP4 (0.67) | DPP4OPRM1DPP8DPP9DPP7 | |
| SCHEMBL29541867 | 0.88 | DPP4 (0.67) | DPP4OPRM1DPP8DPP9DPP7 | |
| Bromide SCHEMBL7274107 | 0.87 | DPP4 (0.66) | DPP4OPRM1DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | claimed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | claimed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | claimed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | claimed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | claimed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | claimed |
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | disclosed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | disclosed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | disclosed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |