Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.69 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.59 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399628 | 0.98 | TDP1 (0.66) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL12019811 | 0.95 | TDP1 (0.63) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL16329976 | 0.91 | TDP1 (0.71) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL29439904 | 0.89 | TDP1 (0.75) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL22630685 | 0.89 | TDP1 (0.71) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL13432796 | 0.88 | TDP1 (0.54) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL14524270 | 0.88 | TDP1 (0.54) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL13311792 | 0.88 | TDP1 (0.54) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL14960415 | 0.88 | TDP1 (0.69) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL24858374 | 0.88 | TDP1 (0.73) | TDP1FOLH1CAPN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189692-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG | 2011-08-04 | — | — | US | disclosed |