Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.73 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29439931 | 1.00 | TDP1 (0.73) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL29439904 | 0.98 | TDP1 (0.75) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL13311908 | 0.91 | TDP1 (0.61) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL12019811 | 0.90 | TDP1 (0.63) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL13311913 | 0.89 | TDP1 (0.58) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL13311883 | 0.89 | TDP1 (0.57) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL31004014 | 0.88 | TDP1 (0.63) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL20417372 | 0.88 | TDP1 (0.85) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL23745168 | 0.88 | TDP1 (0.85) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL12372458 | 0.88 | TDP1 (0.85) | TDP1FOLH1CAPN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000834-A1 | PHYSIOLOGICALLY ACTIVE SUBSTANCE BOUND TO BIOTIN MOIETY, AND COMPOSITION FOR ORAL ADMINISTRATION INCLUDING SAME | D&D PHARMATECH, INC. (KP) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000834-A1 | PHYSIOLOGICALLY ACTIVE SUBSTANCE BOUND TO BIOTIN MOIETY, AND COMPOSITION FOR ORAL ADMINISTRATION INCLUDING SAME | BTD, FABP2, PLPBP | TDP1 4587/4885FOLH1 505/4885CAPN1 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.