Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MDM4 | O15151 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769542 | 0.91 | POLB (0.77) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL30288146 | 0.91 | POLB (0.77) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL28195774 | 0.89 | POLB (0.64) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL5723835 | 0.89 | POLB (0.64) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL30586983 | 0.88 | POLB (0.62) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL26114052 | 0.88 | POLB (0.62) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL27527542 | 0.88 | HDAC2 (0.72) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL14128773 | 0.88 | NPC1 (0.83) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL28316791 | 0.87 | POLB (0.57) | POLBHPGDMAPTNPC1RAB9A | |
| Iodide SCHEMBL30758631 | 0.86 | MAPT (0.84) | POLBHPGDMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | POLB 783/4885HPGD 1140/4885MAPT 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.