Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330697 | 0.86 | ADK (0.49) | ADKHIF1ASLC29A1 | |
| SCHEMBL16330698 | 0.85 | ADK (0.47) | ADKHIF1APAX8SLC29A1 | |
| SCHEMBL16330666 | 0.85 | HIF1A (0.65) | ADKHIF1APAX8SLC29A1 | |
| SCHEMBL16330701 | 0.84 | ADK (0.46) | ADKHIF1APAX8SLC29A1 | |
| SCHEMBL16330695 | 0.82 | ADK (0.47) | ADKHIF1APAX8SLC29A1 | |
| SCHEMBL16330699 | 0.82 | ADK (0.44) | ADKHIF1APAX8SLC29A1CA2 | |
| SCHEMBL16330765 | 0.81 | HIF1A (0.54) | ADKHIF1APAX8 | |
| SCHEMBL16330687 | 0.80 | HIF1A (0.50) | ADKHIF1APAX8 | |
| SCHEMBL13066105 | 0.77 | ADK (0.55) | ADKHIF1APAX8CA2 | |
| SCHEMBL16330668 | 0.77 | HIF1A (0.66) | ADKHIF1APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018010-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | ENZON PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018010-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | VEGFA, MKI67, PCNA | ADK 104/4885HIF1A 922/4885PAX8 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.