Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733884 | 0.85 | DGAT1 (0.43) | DGAT1GABRA2GABRB2ALDH1A1GAA | |
| SCHEMBL13733546 | 0.84 | DGAT1 (0.61) | DGAT1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL30824981 | 0.83 | DGAT1 (0.45) | DGAT1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL19780512 | 0.82 | DGAT1 (0.60) | DGAT1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL16661173 | 0.82 | DGAT1 (0.69) | DGAT1GABRA2GABRB2ALDH1A1NPC1 | |
| SCHEMBL19780156 | 0.82 | DGAT1 (0.59) | DGAT1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL13734316 | 0.81 | DGAT1 (0.58) | DGAT1ALDH1A1TSHRMAPK1KMT2A | |
| SCHEMBL20531461 | 0.80 | DGAT1 (0.57) | DGAT1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL19780155 | 0.80 | DGAT1 (0.57) | DGAT1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL15293975 | 0.80 | DGAT1 (0.77) | DGAT1GABRA2GABRB2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699561-B1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORP (FI) | 2015-06-03 | — | — | EP | disclosed |
| US-8921378-B2 | Androgen receptor modulating carboxamides | ORION CORPORATION (FI) | 2014-12-30 | — | — | US | disclosed |