Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165912 | 0.91 | ESR1 (0.66) | ESR1ESR2TDP1TP53LMNA | |
| SCHEMBL9065911 | 0.91 | ESR1 (0.66) | ESR1ESR2TDP1TP53LMNA | |
| SCHEMBL29393324 | 0.90 | ESR1 (0.69) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL30165897 | 0.90 | ESR1 (0.69) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL4200651 | 0.90 | ESR1 (0.69) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL9849920 | 0.84 | ESR2 (0.61) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL9066039 | 0.83 | ESR1 (0.59) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL27991648 | 0.83 | ESR1 (0.51) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL5386114 | 0.81 | ESR1 (0.71) | ESR1ESR2TDP1TP53MEN1 | |
| SCHEMBL17532659 | 0.80 | ESR1 (0.59) | ESR1ESR2TDP1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2818494-B1 | POLYCARBONATE COPOLYMER | IDEMITSU KOSAN CO (JP) | 2018-12-26 | — | — | EP | disclosed |
| US-9458291-B2 | Polycarbonate copolymer | IDEMITSU KOSAN CO., LTD. (JP) | 2016-10-04 | — | — | US | disclosed |
| US-20150010859-A1 | POLYCARBONATE COPOLYMER | IDEMITSU KOSAN CO., LTD. (JP) | 2015-01-08 | — | — | US | disclosed |
| EP-2818494-A1 | POLYCARBONATE COPOLYMER | Idemitsu Kosan Co., Ltd (JP) | 2014-12-31 | — | — | EP | disclosed |