SCHEMBL9849920

SCHEMBL9849920

CC1CCC(c2ccc(O)cc2)(c2ccc(O)cc2)CC1.Cc1cc(C2(c3ccc(O)c(C)c3)CCC(C)CC2)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 10/20 0.61
ESR1 P03372 7/20 0.61
ACHE P22303 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.35
LMNA P02545 3/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
XBP1 P17861 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALOX12 P18054 1/20 0.33
CETP P11597 1/20 0.33
PTPN1 P18031 1/20 0.33
PTGS2 P35354 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393324 0.94 ESR1 (0.69) ESR2ESR1ACHETDP1TP53
SCHEMBL4200651 0.94 ESR1 (0.69) ESR2ESR1ACHETDP1TP53
SCHEMBL30165897 0.94 ESR1 (0.69) ESR2ESR1ACHETDP1TP53
SCHEMBL30375487 0.87 ESR2 (0.59) ESR2ESR1CYP2C9
SCHEMBL3807813 0.87 ESR2 (0.59) ESR2ESR1CYP2C9
SCHEMBL237553 0.85 ESR2 (0.59) ESR2ESR1MAPTALDH1A1CYP1A2
SCHEMBL16332293 0.84 ESR1 (0.60) ESR2ESR1ACHETDP1TP53
SCHEMBL1129752 0.83 ESR1 (0.87) ESR2ESR1ACHETDP1TP53
SCHEMBL14760430 0.83 ESR1 (0.87) ESR2ESR1ACHETDP1TP53
SCHEMBL23241904 0.82 ACHE (0.61) ESR2ESR1ACHELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413190-A2 Polycarbonates prepared from n-alkyl substituted cyclohexylidene diphenols BAYER AG (DE) 1991-02-20 EP disclosed