Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28136051 | 0.95 | CA1 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL4839463 | 0.95 | CA1 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL1315939 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1647652 | 0.89 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL17888739 | 0.89 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL2945248 | 0.89 | — | — | |
| Bicarbonate SCHEMBL20135784 | 0.89 | — | — | |
| Bicarbonate SCHEMBL21518592 | 0.89 | — | — | |
| Bicarbonate SCHEMBL9253659 | 0.89 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL9485142 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444305-B1 | METHOD OF PREPARING CORE-SHELL ZINC OXIDE PARTICLES | PAN CONTINENTAL CHEMICAL CO LTD (TW) | 2021-10-20 | — | — | EP | claimed |
| US-10465075-B2 | Method of preparing core-shell zinc oxide particles | PAN-CONTINENTAL CHEMICAL CO., LTD. (TW) | 2019-11-05 | — | — | US | claimed |
| US-20190055407-A1 | Method of Preparing Core-Shell Zinc Oxide Particles | PAN-CONTINENTAL CHEMICAL CO., LTD. (TW) | 2019-02-21 | — | — | US | claimed |
| EP-3444305-A1 | METHOD OF PREPARING CORE-SHELL ZINC OXIDE PARTICLES | Pan-continental Chemical Co., Ltd. (TW) | 2019-02-20 | — | — | EP | claimed |
| EP-3444305-B1 | METHOD OF PREPARING CORE-SHELL ZINC OXIDE PARTICLES | PAN CONTINENTAL CHEMICAL CO LTD (TW) | 2021-10-20 | — | — | EP | disclosed |
| US-10465075-B2 | Method of preparing core-shell zinc oxide particles | PAN-CONTINENTAL CHEMICAL CO., LTD. (TW) | 2019-11-05 | — | — | US | disclosed |
| US-20190055407-A1 | Method of Preparing Core-Shell Zinc Oxide Particles | PAN-CONTINENTAL CHEMICAL CO., LTD. (TW) | 2019-02-21 | — | — | US | disclosed |
| EP-3444305-A1 | METHOD OF PREPARING CORE-SHELL ZINC OXIDE PARTICLES | Pan-continental Chemical Co., Ltd. (TW) | 2019-02-20 | — | — | EP | disclosed |
| CN-107140678-B | A kind of wet process technique of high-purity feed grade high-efficiency multiple zinc oxide | 四川康泰祥生物科技有限公司 | 2018-01-23 | — | — | CN | disclosed |
| US-20110152425-A1 | FLOOR POLISH COMPOSITIONS | TYSAK THEODORE | 2011-06-23 | — | — | US | disclosed |
| EP-2336258-A2 | Floor polish compositions | Rohm and Haas Company (US) | 2011-06-22 | — | — | EP | disclosed |
| US-7932313-B2 | Aqueous compositions with polyvalent metal ions and dispersed polymers | ROHM AND HAAS COMPANY (US) | 2011-04-26 | — | — | US | disclosed |
| US-20080114114-A1 | Aqueous compositions with polyvalent metal ions and dispersed polymers | EICHMAN HENRY J | 2008-05-15 | — | — | US | disclosed |
| US-20050288411-A1 | Aqueous compositions with polyvalent metal ions and dispersed polymers | ROHM AND HAAS COMPANY | 2005-12-29 | — | — | US | disclosed |
| EP-1609830-A1 | Aqueous compositions with polyvalent metal ions and dispersed polymers | Rohm and Haas Company (US) | 2005-12-28 | — | — | EP | disclosed |