Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28136051 | 1.00 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL1633285 | 0.95 | CA4 (0.42) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL3623405 | 0.90 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9576856 | 0.90 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL2058500 | 0.90 | — | — | |
| Bicarbonate SCHEMBL6032220 | 0.90 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL17888738 | 0.90 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL225640 | 0.90 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL3397287 | 0.90 | CA4 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8025641 | 0.90 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054642-B2 | Fast drying, high build, sag-resistant compositions, coatings, two-component pack and coating process | BASF SE (DE) | 2024-08-06 | — | — | US | claimed |
| EP-3658637-B1 | AQUEOUS COATING COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-10-25 | — | — | EP | claimed |
| US-11542405-B2 | Aqueous coating composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-01-03 | — | — | US | claimed |
| CN-110997833-B | Aqueous coating composition | 陶氏环球技术有限责任公司 | 2022-01-18 | — | — | CN | claimed |
| US-20210102087-A1 | AQUEOUS COATING COMPOSITION | ROHM AND HAAS COMPANY | 2021-04-08 | — | — | US | claimed |
| US-20200347242-A1 | FAST DRYING, HIGH BUILD, SAG-RESISTANT COMPOSITIONS, COATINGS, TWO-COMPONENT PACK AND COATING PROCESS | BASF SE (DE) | 2020-11-05 | — | — | US | claimed |
| EP-3710537-A1 | FAST DRYING, HIGH BUILD, SAG-RESISTANT COMPOSITIONS, COATINGS, TWO-COMPONENT PACK AND COATING PROCESS | BASF SE (DE) | 2020-09-23 | — | — | EP | claimed |
| CN-111527155-A | Quick-drying, mastic, sag resistant compositions, coatings, two-component packaging and coating processes | 巴斯夫欧洲公司 | 2020-08-11 | — | — | CN | claimed |
| EP-3658637-A1 | AQUEOUS COATING COMPOSITION | Dow Global Technologies LLC (US) | 2020-06-03 | — | — | EP | claimed |
| CN-110997833-A | Aqueous coating composition | 陶氏环球技术有限责任公司 | 2020-04-10 | — | — | CN | claimed |
| WO-2019019077-A1 | AQUEOUS COATING COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-01-31 | — | — | WO | claimed |
| EP-0180319-B1 | WASHOUT RESISTANT COATING OR CAULKING COMPOSITIONS AND APPLICATIONS THEREOF | ROHM AND HAAS COMPANY (US) | 1989-03-15 | — | — | EP | claimed |
| EP-0180319-A1 | Washout resistant coating or caulking compositions and applications thereof | ROHM AND HAAS COMPANY (US) | 1986-05-07 | — | — | EP | claimed |
| US-4571415-A | Washout resistant coatings | ROHM AND HAAS COMPANY (US) | 1986-02-18 | — | — | US | claimed |
| EP-4479460-B1 | FREE STANDING FILM | DOW SILICONES CORP (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4479013-B1 | PERSONAL CARE POD | DOW SILICONES CORP (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4642861-A1 | COATING COMPOSITION AND METHOD OF PREPARING COATING COMPOSITION | Dow Global Technologies LLC (US) | 2025-11-05 | — | — | EP | disclosed |
| US-4339370-A | ZINC AMMONIUM CARBONATE, WATERPROOFING | SCOTT BADER COMPANY LIMITED (GB) | 1982-07-13 | — | — | US | disclosed |
| EP-0035353-A2 | Highly filled crosslinkable emulsion polymer compositions | SCOTT BADER COMPANY LIMITED (GB) | 1981-09-09 | — | — | EP | disclosed |
| US-4203859-A | ACRYLIC POLYMER, METAL IONS, AMMONIA OR A VOLATILE AMINE | ROHM AND HAAS COMPANY (US) | 1980-05-20 | — | — | US | disclosed |