Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634410 | 0.87 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL12723452 | 0.85 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5044623 | 0.81 | PDE1B (0.43) | ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL1632739 | 0.76 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL17331649 | 0.75 | ALDH1A1 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL17341812 | 0.73 | PDCD1 (0.43) | ALDH1A1NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL1776316 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL31508111 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5048184 | 0.73 | HRH3 (0.50) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL2068336 | 0.73 | HRH3 (0.49) | MEN1KMT2AALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932393-B2 | Insecticidal (heteroarylalky)alkane thio and oxo amine derivatives | FMC CORPORATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20100261757-A1 | Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives | FMC CORPORATION | 2010-10-14 | — | — | US | disclosed |
| WO-2007085356-A2 | INSECTICIDAL (HETEROARYLALKYL)ALKANE THIO AND OXO AMINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261757-A1 | Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives | DDT, AKR7A2, TAAR1 | MEN1 4602/4885KMT2A 1055/4885SMN1; SMN2 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.