Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
| ▸ | PIK3R5 | Q8WYR1 | 4/20 | 0.32 |
| ▸ | PIK3R3 | Q92569 | 4/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334311 | 0.92 | CNR2 (0.34) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377805 | 0.90 | PIK3CD (0.35) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16334443 | 0.89 | PIK3CD (0.33) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17783226 | 0.87 | PIK3CD (0.36) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377729 | 0.86 | PIK3CD (0.34) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16340545 | 0.85 | CCNA2 (0.35) | — | |
| SCHEMBL16377733 | 0.85 | PIK3CD (0.34) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17789666 | 0.85 | PIK3CD (0.33) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377776 | 0.84 | PIK3CD (0.34) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL22626519 | 0.84 | PIK3CD (0.33) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | Merck Patent GmbH (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014209980-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |