Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339510 | 0.90 | CCNA2 (0.34) | CCNA2CDK2CCNA1 | |
| SCHEMBL16377792 | 0.88 | CCNA2 (0.36) | CCNA2CDK2CCNA1 | |
| SCHEMBL17783243 | 0.87 | CCNA2 (0.35) | CCNA2CDK2CCNA1 | |
| SCHEMBL16334446 | 0.85 | PIK3CD (0.32) | — | |
| SCHEMBL16333638 | 0.84 | CCNA2 (0.39) | CCNA2CDK2CCNA1 | |
| SCHEMBL16333930 | 0.82 | CCNA2 (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL16377823 | 0.82 | CCNA2 (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL16377975 | 0.81 | CCNA2 (0.36) | CCNA2CDK2CCNA1 | |
| SCHEMBL16377700 | 0.81 | CCNA2 (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL16333609 | 0.81 | CCNA2 (0.39) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | Merck Patent GmbH (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014209980-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |