SCHEMBL16336184

SCHEMBL16336184

O=S(=O)(O)c1ccc(-c2c3nc(c(-c4ccc(S(=O)(=O)O)cc4)c4ccc([nH]4)c(-c4ccc(S(=O)(=O)O)cc4)c4nc(c(-c5ccc(S(=O)(=O)O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1.[NaH]

nearest known ligand 0.94

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 1/20 0.94
▸ TOP1 P11387 4/20 0.59
▸ CYCS P99999 3/20 0.57
▸ TERT O14746 5/20 0.52
▸ ABCG2 Q9UNQ0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15004676 1.00 ENPP2 (0.94) ENPP2TOP1CYCSTERTABCG2
SCHEMBL15006289 0.98 ENPP2 (0.91) ENPP2TOP1CYCSTERTABCG2
SCHEMBL218702 0.98 ENPP2 (0.97) ENPP2TOP1CYCSTERTABCG2
SCHEMBL29368142 0.98 ENPP2 (0.97) ENPP2TOP1CYCSTERTABCG2
Water SCHEMBL23522817 0.97 ENPP2 (0.94) ENPP2TOP1CYCSTERTABCG2
SCHEMBL6139703 0.97 ENPP2 (0.94) ENPP2TOP1CYCSTERTABCG2
Water SCHEMBL9870167 0.97 ENPP2 (0.94) ENPP2TOP1CYCSTERTABCG2
SCHEMBL17768419 0.97 ENPP2 (0.94) ENPP2TOP1CYCSTERTABCG2
Tetraphenylporphine Tetrasulfonic Acid SCHEMBL20456165 0.97 ENPP2 (1.00) ENPP2TOP1CYCSTERTABCG2
Ammonia Solution, Strong SCHEMBL3001889 0.97 ENPP2 (0.94) ENPP2TOP1CYCSTERTABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12019316-B2 Color-balanced lenses exhibiting reduced blue light transmittance ESSILOR INTERNATIONAL (FR) 2024-06-25 — — US disclosed
EP-3296799-B1 OPTICAL ARTICLE WITH BLUE CUT, HIGH UV CUT AND HIGH CLARITY ESSILOR INT (FR) 2024-05-22 — — EP disclosed
US-11635547-B2 Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive ESSILOR INTERNATIONAL (FR) 2023-04-25 — — US disclosed
EP-3497488-B2 OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE ESSILOR INT (FR) 2023-03-22 — — EP disclosed
EP-3327091-B1 EPOXY FUNCTIONAL COMPOSITION PROTECTING DYES FROM PHOTO-DEGRADATION AND CURED COATINGS PREPARED THEREFROM ESSILOR INT (FR) 2023-01-18 — — EP disclosed
EP-3296351-B1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE ESSILOR INT (FR) 2022-06-29 — — EP disclosed
US-11327202-B2 Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive ESSILOR INTERNATIONAL (FR) 2022-05-10 — — US disclosed
US-11214695-B2 Epoxy functional composition protecting dyes from photo-degradation and cured coatings prepared therefrom ESSILOR INTERNATIONAL (FR) 2022-01-04 — — US disclosed
US-11204445-B2 Ophthalmic lens comprising an encapsulated light-absorbing additive ESSILOR INTERNATIONAL (FR) 2021-12-21 — — US disclosed
US-20210181532-A1 COLOR-BALANCED LENSES EXHIBITING REDUCED BLUE LIGHT TRANSMITTANCE ESSILOR INTERNATIONAL (FR) 2021-06-17 — — US disclosed
EP-3371647-A1 OPTICAL ARTICLE CUTTING BLUE LIGHT Essilor International (FR) 2018-09-12 — — EP disclosed
WO-2018095679-A1 EPOXY FUNCTIONAL COMPOSITION PROTECTING DYES FROM PHOTO-DEGRADATION AND CURED COATINGS PREPARED THEREFROM ESSILOR INTERNATIONAL (FR) 2018-05-31 — — WO disclosed
EP-3327091-A1 EPOXY FUNCTIONAL COMPOSITION PROTECTING DYES FROM PHOTO-DEGRADATION AND CURED COATINGS PREPARED THEREFROM Essilor International (FR) 2018-05-30 — — EP disclosed
WO-2018055010-A1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE ESSILOR INTERNATIONAL (FR) 2018-03-29 — — WO disclosed
WO-2018054994-A1 POLYCARBONATE RESIN WITH IMPROVED BLUE-CUT AND NEUTRAL COLOR ESSILOR INTERNATIONAL (FR) 2018-03-29 — — WO disclosed
EP-3296799-A1 OPTICAL ARTICLE WITH BLUE CUT, HIGH UV CUT AND HIGH CLARITY Essilor International (FR) 2018-03-21 — — EP disclosed
EP-3296351-A1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE Essilor International (FR) 2018-03-21 — — EP disclosed
EP-3296352-A1 POLYCARBONATE RESIN WITH IMPROVED BLUE-CUT AND NEUTRAL COLOR Essilor International (FR) 2018-03-21 — — EP disclosed
EP-3282290-A1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE Essilor International (FR) 2018-02-14 — — EP disclosed
US-20150002809-A1 OPHTHALMIC FILTER ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2015-01-01 — — US disclosed
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