Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL11509952 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL3238826 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL2916896 | 0.96 | CA4 (0.50) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL5712834 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL22948 | 0.92 | — | — | |
| Glycine SCHEMBL7199765 | 0.92 | — | — | |
| Glycine SCHEMBL8149628 | 0.92 | — | — | |
| Glycine SCHEMBL21747591 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL33936 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL18886797 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856824-B1 | COATED HEAT-SHRINKABLE FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-10-19 | — | — | EP | disclosed |
| US-11208591-B2 | Hydrophobic coating of particulates for enhanced well productivity | PREFERRED TECHNOLOGY, LLC (US) | 2021-12-28 | — | — | US | disclosed |
| US-20210323742-A1 | COATED HEAT-SHRINKABLE FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-10-21 | — | — | US | disclosed |
| EP-3856824-A1 | COATED HEAT-SHRINKABLE FILMS | Dow Global Technologies LLC (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-112714779-A | Coated heat shrinkable film | 陶氏环球技术有限责任公司 | 2021-04-27 | — | — | CN | disclosed |
| EP-3099749-B1 | AQUEOUS SURFACE COATING COMPOSITION AND MODIFIED PARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2021-02-24 | — | — | EP | disclosed |
| CN-105940062-B | Aqueous surface coating composition and modified particles | 3M创新有限公司 | 2020-04-10 | — | — | CN | disclosed |
| WO-2020068422-A1 | COATED HEAT-SHRINKABLE FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-04-02 | — | — | WO | disclosed |
| US-10465079-B2 | Aqueous surface coating composition and modified particles comprising hydrophobic and hydrophilic moieties | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190270931-A1 | PROPPANTS WITH IMPROVED DUST CONTROL | DOW GLOBAL TECHNOLOGIES LLC | 2019-09-05 | — | — | US | disclosed |
| EP-0900833-A1 | Polymer for improving the burnish response of a floor polish | ROHM AND HAAS COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0122788-B1 | SELF-LEVELING POLISH COMPOSITIONS AND POLYMER COMPOSITIONS USEFUL THEREIN | ROHM AND HAAS COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0120712-B1 | POLISH COMPOSITIONS AND POLISH VEHICLES USEFUL THEREIN | ROHM AND HAAS COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |
| US-4517330-A | ACID COPOLYMER CROSSLINKING WITH TRANSITION METAL | ROHM AND HAAS COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0122788-A2 | Self-leveling polish compositions and polymer compositions useful therein | ROHM AND HAAS COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |
| EP-0120712-A2 | Polish compositions and polish vehicles useful therein | ROHM AND HAAS COMPANY (US) | 1984-10-03 | — | — | EP | disclosed |
| US-4460734-A | ETHYLENE OXIDE FATTY ALCOHOL ADDUCT, ADDITION POLYMER | ROHM AND HAAS COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4168255-A | Oligomeric aqueous finishes | ROHM AND HAAS COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4145465-A | CROSSLINKED ADDITION POLYMER | ROHM AND HAAS COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4017662-A | LOW MOLECULAR WEIGHT HYDROPHILIC ADDITION COPOLYMER | ROHM AND HAAS COMPANY (US) | 1977-04-12 | — | — | US | disclosed |