Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL2916896 | 0.96 | CA4 (0.50) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL33936 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL22948 | 0.92 | — | — | |
| Glycine SCHEMBL9244783 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL5712834 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL7632674 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL8149628 | 0.92 | — | — | |
| Glycine SCHEMBL1633657 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL2708039 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL7199765 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612542-B1 | ENERGY-EFFICIENT SOLVENT-FREE METHOD FOR PRODUCING METAL CHELATES | TECHNISCHE UNIV CLAUSTHAL (DE) | 2026-04-22 | — | — | EP | claimed |
| US-12398157-B2 | Energy-efficient solvent-free method for producing metal chelates | TECHNISCHE UNIVERSITAT CLAUSTHAL (DE) | 2025-08-26 | — | — | US | claimed |
| US-20230219980-A1 | ENERGY-EFFICIENT SOLVENT-FREE METHOD FOR PRODUCING METAL CHELATES | TECHNISCHE UNIVERSITAT CLAUSTHAL (DE) | 2023-07-13 | — | — | US | claimed |
| CN-110770246-B | Energy-saving solvent-free method for producing metal chelate | 克劳斯塔尔工业大学 | 2023-06-06 | — | — | CN | claimed |
| EP-3612542-A1 | ENERGY-EFFICIENT SOLVENT-FREE METHOD FOR PRODUCING METAL CHELATES | Technische Universität Clausthal (DE) | 2020-02-26 | — | — | EP | claimed |
| US-12398157-B2 | Energy-efficient solvent-free method for producing metal chelates | TECHNISCHE UNIVERSITAT CLAUSTHAL (DE) | 2025-08-26 | — | — | US | disclosed |
| US-20230219980-A1 | ENERGY-EFFICIENT SOLVENT-FREE METHOD FOR PRODUCING METAL CHELATES | TECHNISCHE UNIVERSITAT CLAUSTHAL (DE) | 2023-07-13 | — | — | US | disclosed |
| CN-110770246-B | Energy-saving solvent-free method for producing metal chelate | 克劳斯塔尔工业大学 | 2023-06-06 | — | — | CN | disclosed |
| US-11649252-B2 | Energy-efficient solvent-free method for producing metal chelates | TECHNISCHE UNIVERSITAT CLAUSTHAL (DE) | 2023-05-16 | — | — | US | disclosed |