Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL44218 | 0.99 | GAA (0.38) | GAAKDM4EALDH1A1GLACA12 | |
| SCHEMBL1923453 | 0.95 | CA12 (0.38) | GAAKDM4EALDH1A1GLACA12 | |
| Hydrochloric Acid SCHEMBL7062212 | 0.94 | CA12 (0.37) | GAAKDM4EALDH1A1GLACA12 | |
| SCHEMBL11036757 | 0.77 | KDM4E (0.33) | GAAKDM4EALDH1A1GLASIRT3 | |
| SCHEMBL8130177 | 0.77 | GAA (0.36) | GAAMAPK8MAPK9MAPK10CYP11B2 | |
| Acetone SCHEMBL538075 | 0.75 | CNR2 (0.41) | KDM4EALDH1A1TDP1MGLLMAPT | |
| Acetone SCHEMBL17732269 | 0.73 | MAPK1 (0.39) | GAAKDM4EMAPK1MGLLL3MBTL1 | |
| Acetone SCHEMBL15923153 | 0.73 | KDM4C (0.53) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL15231891 | 0.73 | RBP4 (0.43) | GAAALDH1A1MGLLMAPTCYP11B2 | |
| SCHEMBL15066588 | 0.72 | KDM4E (0.42) | GAAKDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49304-E1 | Compositions and method for multiplex biomarker profiling | UNIVERSITY OF WASHINGTON (US) | 2022-11-22 | — | — | US | disclosed |
| US-11353448-B2 | Methods and compositions for quantifying metabolites and proteins from single cells | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210381007-A1 | METHODS AND COMPOSITIONS FOR CRISPR EDITING OF CELLS AND CORRELATING THE EDITS TO A RESULTING CELLULAR NUCLEIC ACID PROFILE | INSCRIPTA, INC. | 2021-12-09 | — | — | US | disclosed |
| US-RE47983-E1 | Compositions and methods for multiplex biomarker profiling | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2020-05-12 | — | — | US | disclosed |
| US-20160238594-A1 | METHODS AND COMPOSITIONS FOR QUANTIFYING METABOLITES AND PROTEINS FROM SINGLE CELLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-08-18 | — | — | US | disclosed |
| US-9376717-B2 | Compositions and methods for multiplex biomarker profiling | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150167064-A1 | COMPOSITIONS AND METHODS FOR MULTIPLEX BIOMARKER PROFILING | UNIVERSITY OF WASHINGTON (US) | 2015-06-18 | — | — | US | disclosed |
| US-8946389-B2 | Compositions and methods for multiplex biomarker profiling | UNIVERSITY OF WASHINGTON (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150004598-A1 | COMPOSITIONS AND METHODS FOR MULTIPLEX BIOMARKER PROFILING | UNIVERSITY OF WASHINGTON (US) | 2015-01-01 | — | — | US | disclosed |