⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554388 | 1.00 | — | — | |
| SCHEMBL7212491 | 0.97 | — | — | |
| SCHEMBL7169193 | 0.77 | — | — | |
| SCHEMBL7175516 | 0.77 | — | — | |
| SCHEMBL7175521 | 0.77 | — | — | |
| SCHEMBL7171674 | 0.75 | — | — | |
| SCHEMBL3366060 | 0.74 | — | — | |
| SCHEMBL7956129 | 0.74 | — | — | |
| SCHEMBL5168798 | 0.74 | — | — | |
| SCHEMBL3366057 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932420-B2 | Lowering intraocular pressure; glaucoma | ALLERGAN, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| EP-1919862-B1 | SULPHONAMIDES OF 7-AMINOHEPTANOIC ACID DERIVATIVES FOR TREATING GLAUCOMA | ALLERGAN INC (US) | 2010-10-06 | — | — | EP | disclosed |
| US-20080167331-A1 | Novel sulfonamides | BURK ROBERT M | 2008-07-10 | — | — | US | disclosed |
| US-7314890-B2 | Sulfonamides | ALLERGAN, INC. (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070043090-A1 | Novel Sulfonamides | ALLERGAN, INC. | 2007-02-22 | — | — | US | disclosed |
| EP-1042283-B1 | OMEGA-CYCLOALKYL-PROSTAGLANDIN E2 DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-20030186939-A1 | Omega-cycloalkyl-prostaglandin E2 derivatives | TANI KOUSUKE (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6613932-B1 | Prostaglandin derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| US-6576785-B1 | ω-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1219601-A1 | PROSTAGLANDIN DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6262293-B1 | CLATHRATE COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| US-6110969-A | Cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO. LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |