Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862851 | 0.89 | DHFR (0.57) | DHFRHTT | |
| SCHEMBL2598775 | 0.81 | KDR (0.48) | — | |
| SCHEMBL2598577 | 0.81 | SYK (0.46) | — | |
| SCHEMBL2598633 | 0.80 | BACE1 (0.43) | DHFR | |
| SCHEMBL2598814 | 0.79 | BACE1 (0.40) | DHFR | |
| SCHEMBL6557495 | 0.79 | DHFR (0.54) | DHFR | |
| SCHEMBL16339568 | 0.78 | DHFR (0.58) | DHFRHTT | |
| SCHEMBL16494310 | 0.77 | CLK2 (0.45) | DHFR | |
| SCHEMBL9829477 | 0.77 | DHFR (0.63) | DHFR | |
| SCHEMBL7119117 | 0.76 | DHFR (0.62) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927547-B2 | Pyrimidine derivatives | NOVIGA RESEARCH AB (SE) | 2015-01-06 | — | — | US | claimed |
| CN-103003264-B | Novel pyrimidine derivatives | CHEMILIA AB | 2014-08-06 | — | — | CN | claimed |
| CN-103003264-B | Novel pyrimidine derivatives | CHEMILIA AB | 2014-08-06 | — | — | CN | disclosed |
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |