Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21199572 | 0.86 | MAPK1 (0.36) | MAPK1P2RX7 | |
| SCHEMBL21199575 | 0.86 | MAPK1 (0.36) | MAPK1P2RX7 | |
| SCHEMBL16339902 | 0.84 | USP30 (0.40) | MAPK1 | |
| SCHEMBL28648680 | 0.84 | USP30 (0.40) | MAPK1 | |
| SCHEMBL16339903 | 0.84 | USP30 (0.40) | MAPK1 | |
| SCHEMBL27174551 | 0.78 | MAPK1 (0.33) | MAPK1P2RX7 | |
| SCHEMBL27174548 | 0.78 | MAPK1 (0.33) | MAPK1P2RX7 | |
| SCHEMBL23991519 | 0.76 | USP30 (0.35) | — | |
| SCHEMBL4068806 | 0.74 | KIF11 (0.36) | MAPK1P2RX7 | |
| SCHEMBL16386337 | 0.73 | USP30 (0.39) | MAPK1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013333-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF HEPATITIS C | MERCK SHARP & DOHME (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-3013333-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF HEPATITIS C | Merck Sharp & Dohme Corp. (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014209729-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF HEPATITIS C | MERCK SHARP & DOHME CORP. (US) | 2014-12-31 | — | — | WO | disclosed |