Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | FDPS | P14324 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857008 | 1.00 | TDP1 (0.58) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL4966397 | 0.93 | TDP1 (0.51) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL6852447 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL19549608 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL8847272 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL15301868 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL8847266 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL2050248 | 0.91 | ALOX5 (0.55) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL22282470 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA | |
| SCHEMBL8847274 | 0.91 | TDP1 (0.50) | TDP1FDPSMAPK1ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013925-B1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LTD (GB) | 2019-08-07 | — | — | EP | disclosed |
| EP-3013925-B1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LTD (GB) | 2019-08-07 | — | — | EP | disclosed |
| US-10125335-B2 | Lubricating compositions containing isoprene based components | CASTROL LIMITED (GB) | 2018-11-13 | — | — | US | disclosed |
| US-20160137945-A1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LIMITED (GB) | 2016-05-19 | — | — | US | disclosed |
| US-20160137945-A1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LIMITED (GB) | 2016-05-19 | — | — | US | disclosed |
| US-20160137945-A1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LIMITED (GB) | 2016-05-19 | — | — | US | disclosed |
| EP-3013925-A1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | Castrol Limited (GB) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014207235-A1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LIMITED (GB) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014207235-A1 | LUBRICATING COMPOSITIONS CONTAINING ISOPRENE BASED COMPONENTS | CASTROL LIMITED (GB) | 2014-12-31 | — | — | WO | disclosed |