SCHEMBL16340710

SCHEMBL16340710

CC(=O)N[C@H]1CNC(=O)C[C@@H](C(C)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSLP Q969D9 16/20 0.58
MC4R P32245 4/20 0.50
MC1R Q01726 4/20 0.50
MC5R P33032 3/20 0.50
MC3R P41968 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16340729 0.95 TSLP (0.58) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340671 0.94 TSLP (0.57) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340418 0.93 TSLP (0.56) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340575 0.93 TSLP (0.56) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340684 0.92 TSLP (0.57) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340572 0.92 TSLP (0.58) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340904 0.91 TSLP (0.56) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340382 0.90 TSLP (0.56) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340903 0.90 TSLP (0.54) TSLPMC4RMC1RMC5RMC3R
SCHEMBL16340843 0.90 TSLP (0.53) TSLPMC4RMC1RMC5RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R TSLP 177/4885MC4R 1/4885MC1R 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.