SCHEMBL1634405

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5679935	1.00	CYP1A2 (0.56)	CYP1A2GRIA2PPARGPLA2G10PLA2G2A
	SCHEMBL10009088	0.87	FOLH1 (0.51)	CYP1A2GRIA2PPARGANPEPERAP2
	SCHEMBL22714101	0.83	GRIA2 (0.55)	CYP1A2GRIA2ANPEPERAP2ERAP1
	SCHEMBL14885274	0.83	CYP1A2 (0.56)	CYP1A2PPARGPLA2G10PLA2G2AFOLH1
	SCHEMBL4337145	0.83	EPHX2 (0.52)	PPARGPPARAEPHX2
	SCHEMBL265063	0.82	CYP1A2 (0.83)	CYP1A2PPARGFOLH1PPARACPA1
	SCHEMBL491524	0.82	CYP1A2 (0.83)	CYP1A2PPARGFOLH1PPARACPA1
	SCHEMBL265514	0.82	CYP1A2 (0.83)	CYP1A2PPARGFOLH1PPARACPA1
	SCHEMBL1068216	0.82	CYP1A2 (0.55)	CYP1A2PPARGPLA2G10PLA2G2AFOLH1
	SCHEMBL14885329	0.82	SLC1A1 (0.57)	CYP1A2PPARGPLA2G10PLA2G2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.