Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | CPA3 | P15088 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989957 | 0.85 | GRIA2 (0.48) | GRIA2ANPEPERAP2ERAP1ENPP2 | |
| SCHEMBL1634405 | 0.83 | CYP1A2 (0.56) | GRIA2ANPEPERAP2ERAP1CYP1A2 | |
| SCHEMBL5679935 | 0.83 | CYP1A2 (0.56) | GRIA2ANPEPERAP2ERAP1CYP1A2 | |
| SCHEMBL4992735 | 0.83 | GRIA2 (0.46) | GRIA2ANPEPERAP2ERAP1ENPP2 | |
| SCHEMBL5171909 | 0.82 | CYP1A2 (0.76) | ANPEPERAP2CYP1A2FOLH1SLC1A3 | |
| SCHEMBL4738634 | 0.82 | CYP1A2 (0.76) | ANPEPERAP2CYP1A2FOLH1SLC1A3 | |
| SCHEMBL558159 | 0.82 | CYP1A2 (0.76) | ANPEPERAP2CYP1A2FOLH1SLC1A3 | |
| SCHEMBL1817242 | 0.82 | PNMT (0.53) | CYP1A2FOLH1TAAR1SLC1A3SLC1A2 | |
| SCHEMBL1817614 | 0.82 | PNMT (0.53) | CYP1A2FOLH1TAAR1SLC1A3SLC1A2 | |
| SCHEMBL1814454 | 0.82 | CYP1A2 (0.50) | ANPEPERAP2CYP1A2FOLH1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725007-B2 | Meta tyrosine derivatives as rho-kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-08-15 | — | — | US | disclosed |
| EP-3728246-B1 | META TYROSINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2021-09-22 | — | — | EP | disclosed |
| US-20200377500-A1 | META TYROSINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377500-A1 | META TYROSINE DERIVATIVES AS RHO-KINASE INHIBITORS | ROCK1, ROCK2, RHOA | GRIA2 3087/4885ANPEP 2244/4885ERAP2 4218/4885 |
| US-11725007-B2 | Meta tyrosine derivatives as rho-kinase inhibitors | ROCK1, ROCK2, RHOA | GRIA2 3087/4885ANPEP 2244/4885ERAP2 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.