Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 0.69 |
| ▸ | INSR | P06213 | 1/20 | 0.69 |
| ▸ | IGF1R | P08069 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | SRC | P12931 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | FLT3 | P36888 | 1/20 | 0.69 |
| ▸ | TEC | P42680 | 1/20 | 0.69 |
| ▸ | TXK | P42681 | 1/20 | 0.69 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.69 |
| ▸ | BMX | P51813 | 1/20 | 0.69 |
| ▸ | JAK3 | P52333 | 1/20 | 0.69 |
| ▸ | ITK | Q08881 | 1/20 | 0.69 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353814 | 0.92 | BTK (1.00) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16344014 | 0.91 | BTK (0.83) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16353753 | 0.91 | BTK (0.83) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16353735 | 0.90 | BTK (0.81) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16353572 | 0.89 | BTK (0.81) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16355174 | 0.89 | BTK (1.00) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL3999908 | 0.89 | BTK (1.00) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16344419 | 0.89 | BTK (1.00) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16353646 | 0.88 | BTK (0.79) | BTKJAK2INSRIGF1RCYP3A4 | |
| SCHEMBL16353556 | 0.87 | BTK (0.78) | BTKJAK2INSRIGF1RCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2824099-A1 | NOVEL TRIAZINE DERIVATIVE | Carna Biosciences Inc. (JP) | 2015-01-14 | — | — | EP | disclosed |
| EP-2824099-A1 | NOVEL TRIAZINE DERIVATIVE | Carna Biosciences Inc. (JP) | 2015-01-14 | — | — | EP | disclosed |
| US-20150011751-A1 | NOVEL TRIAZINE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2015-01-08 | — | — | US | disclosed |
| US-20150011751-A1 | NOVEL TRIAZINE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2015-01-08 | — | — | US | disclosed |
| CN-104169260-A | Novel triazone derivative | CARNA BIOSCIENCES INC | 2014-11-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011751-A1 | NOVEL TRIAZINE DERIVATIVE | HDAC5, IL5, AGTR2 | BTK 2663/4885JAK2 54/4885INSR 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.