Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 15/20 | 0.71 |
| ▸ | OPRM1 known ✓ | P35372 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | HRH1 | P35367 | 3/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.62 |
| ▸ | HTR2B | P41595 | 3/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107035 | 0.93 | SLC6A4 (0.82) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| SCHEMBL5015289 | 0.93 | SLC6A4 (0.82) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL4942454 | 0.92 | SLC6A4 (0.79) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL17685574 | 0.92 | SLC6A4 (0.79) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| SCHEMBL32660752 | 0.85 | SLC6A4 (0.69) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| Fluoxetine SCHEMBL8722258 | 0.85 | SLC6A4 (0.88) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| SCHEMBL15257454 | 0.85 | SLC6A4 (0.68) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| SCHEMBL5011928 | 0.84 | SLC6A4 (1.00) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| SCHEMBL8197696 | 0.84 | SLC6A4 (1.00) | SLC6A4CYP2D6KMT2ALMNASLC6A2 | |
| SCHEMBL12546452 | 0.84 | SLC6A4 (0.67) | SLC6A4CYP2D6KMT2ALMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015001565-A2 | \"AN IMPROVED PROCESS FOR THE PREPARATION OF 3-ARYLOXY-3- PHENYLPROPYLAMINE AND SALT THEREOF\ | ZCL CHEMICALS LIMITED (IN) | 2015-01-08 | — | — | WO | disclosed |