Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.81 |
| ▸ | GNA15 | P30679 | 1/20 | 0.81 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.81 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.81 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.81 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16347531 | 1.00 | FFAR1 (0.81) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16388685 | 0.94 | FFAR1 (0.71) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16388358 | 0.93 | FFAR1 (0.70) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16388392 | 0.93 | FFAR1 (0.70) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16347718 | 0.90 | FFAR1 (0.75) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16347720 | 0.90 | FFAR1 (0.75) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| Fasiglifam SCHEMBL16448782 | 0.90 | FFAR1 (1.00) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| Fasiglifam SCHEMBL31192643 | 0.90 | FFAR1 (1.00) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| Fasiglifam SCHEMBL16448793 | 0.90 | FFAR1 (1.00) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| Fasiglifam SCHEMBL29360096 | 0.90 | FFAR1 (1.00) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507921-B | Benzocyclobutene derivative and preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104507921-A | Benzocyclobutene derivative and preparation method and pharmaceutical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | disclosed |
| WO-2015000412-A1 | BENZOCYCLOBUTENE DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 (CN) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015000412-A1 | BENZOCYCLOBUTENE DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 (CN) | 2015-01-08 | — | — | WO | disclosed |